Human Sera
Cayman Chemical RaltItrexed 50mg
An inhibitor of thymidylate synthase (Ki = 62 nM); inhibits the growth of L1210 mouse lymphocytic leukemia cells in vitro (IC50 = 8 nM); reduces thymidylate synthase activity and completely eliminates tumors in a mouse L1210:ICR ascitic tumor model at 4 mg/kg; reduces tumor growth and the number of metastases in an HCT116-luc mouse xenograft model
Cayman Chemical GastrodIa elta Gastrodn 100mg
A phenolic glycoside with diverse biological activities; reduces Aβ42-induced cell death of rat hippocampal neurons and BV-2 mouse microglia; improves learning and memory in various transgenic mouse models of Alzheimer's disease; reduces motor deficits and loss of dopaminergic neurons in a rat model of Parkinson's disease; reduces seizure duration and intensity in a rat model of pentylenetetrazole-kindling chronic epileptic seizures from 50-200 mg/kg; increases social interaction and decreases marble burying and grooming behaviors, as well as restores inhibitory synaptic transmission and GAT1 and α5 subunit-containing GABAA expression in the basolateral amygdala in a mouse model of valproic acid-induced autistic-like phenotypes at 100 mg/kg; increases biomechanical bone strength in a rat model of dexamethasone-induced osteoporosis; inhibits ethanol-induced hepatocellular apoptosis and restores liver function in a rat model of alcoholic liver disease
Cayman Chemical LGulanosylcaldarchaetidyl 50mg
The main polar lipid of the archaeon T. acidophilum; cellular levels of β-L-gulopyranosyl-caldarchaetidyl-glycerol in T. acidophilum HO-62 positively and negatively correlate with increases in culture pH and temperature, respectively; has been used as a standard for the quantification of polar lipids extracted from T. acidophilum HO-62
Cayman Chemical 2pToluIdInylnaphthylen6s 50mg
An anionic fluorescent probe for the conformational state of proteins; ex/em = 321/446 nm, respectively; has been used to determine the pKa values of LNPs
Meso Scale Discovery R-PLEX Human PR/PGR ASYQP
The R-Plex Human PR/PGR Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures the levels of progesterone receptor (PR) and progesterone (PGR) in human serum plasma and cell culture supernatants This 10-plex assay utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The assay can be run on Meso Scale Diagnostic s QuickPlex SQ 120 instrument and MESO QuickPlex SQ 120 Plates in as little as 3 hours This assay allows for the quantitative measurement of PR and PGR levels which can aid in monitoring hormone therapy and diagnosing hormone-related disorders
Cayman Chemical 6 7 4TrIhydroxyIsoflavon 100mg
An active metabolite of daidzein; suppresses anchorage-dependent and -independent growth of HCT116 and DLD-1 colon cancer cells, as well as induces cell cycle arrest at the S and G2/M phases in HCT116 cells from 12.5-100 µM; inhibits MDI-induced adipogenesis in 3T3-L1 preadipocytes at 40 and 80 µM; reverses scopolamine-induced memory impairments and increases hippocampal BDNF and CREB levels in mice at 5 mg/kg; prevents LPS-induced bone loss in mice
Cayman Chemical N2 N2-DImethylgunosIn 50mg
A methylated purine nucleoside; formed during the degradation of tRNA; serum levels are elevated in patients with AMML or large cell lung carcinoma
Cayman Chemical SecnIdazole 100mg
A 5-nitroimidazole derivative with antiparasitic and antibiotic activity; exhibits a mean minimum inhibitory concentration of 2.59 µM against 16 clinical isolates of B. fragilis
Cayman Chemical QuercetIn 3ODGlucose7O 50mg
A flavonoid glycoside with lipid-lowering activity; reduces sodium oleate-induced increases in triglyceride levels in HepG2 cells at 30 µM
Cayman Chemical CID-2818500 50mg
An inhibitor of PRMT1 (IC50 = 11 μM in a histone H4 methylation assay); inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, at 10 and 100 μM
Cayman Chemical 6 2 4-TrImethoxyflavon 50mg
A flavonoid; inhibits benzo[a]pyrene-induced AhR-dependent transcription in a reporter assay at 2 and 10 µM; decreases LPS-induced production of TNF-α in THP-1 cells (IC50 = 47.7 UG/ml); inhibits cell migration and invasion of HN-30 HNSCC cells at 10 µM
Cayman Chemical DIclofensInhydrochlorIde 50mg
A potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively; intended for research and forensic applications
Cayman Chemical Paclobutrazol 100mg
A triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins
Cayman Chemical CItrulInated Hsp70R155 Po 1ea
Immunogen: Peptide from the internal region of human Hsp70 containing a citrulline at residue 155 • Host: Rabbit • Cross Reactivity: (+) Citrullinated Hsp70, Citrullinated GRP78; (-) Hsp70, other citrullinated Hsp proteins • Species Reactivity: (+) Human; other species not tested • Applications: ELISA and WB